Dr. N.C.Padhi was born in 1937, 17th of August, at Brahmapur to Late Sri RP.Padhi and Pratima. He belongs to a family of Government officers and academics. His father was Vice Chancellor of Brahmapur and Rajasthan Universities during the 1960s and seventies after retiring as Chief Secretary of Orissa. Dr. Padhi was educated at Cuttack, Balasore, Sambalpur and Puri in schools and Ravenshaw College and SCB Medical at Cuttack. He specialized in Surgery and received his Master of Surgery degree from the prestigious Delhi University and Maulana Azad Medical College, Delhi. He joined the Orissa Medical Education Service in1964 and worked at all the three Medical Colleges of the state but mostly at MKCG Medical College at Brahmapur. The last five years of his career as a Medical Teacher was at SCB Medical College at Cuttack, from where he took his retirement from Government Service in 1995. He was Professor and Head of Surgery and MedicalSuperintendent at the time.   

He is socially very active and his organizational skills have been appreciated. He has been a member of Lions Club of Berhampur since 1968 and has held the coveted post of District Governor during 1987-88. He has organized several conferences at Brahmapur and Cuttack. The Silver Jubilee Celebrations of MKCG Medical College, Brahmapur and the huge All India Surgeons Conference at Cuttack are memorable events organized by him. He has been the President of the all Orissa Medical College Teacher's Association, the Association Of Surgeons, Orissa Chapter and the Indian Medical Association of the Orissa State.

He is associated with several organizations locally and nationally. He is still actively practicing as a surgeon, though on a limited scale,and is in charge of the Red Cross Hospital for the last 9years and the District Disabled Rehab Centre, Ganjam.

He is married to Ranjita the daughter of the famous Kabiraj Krushna Ch. Tripathy of Aska. He has a son who is a senior IAS officer of the State and two daughters, both doctors and well settled.